ABIN955378

antibody from antibodies-online

Targeting: TTC8 BBS8, RP51

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN955378

Provider

antibodies-online

Product name

anti-Tetratricopeptide Repeat Domain 8 (TTC8) (AA 17-46), (N-Term) antibody

Antibody type

Polyclonal

Description

Protein A column followed by peptide affinity purification

Reactivity

Human

Host

Rabbit

Epitope

N-Term, AA 17-46

Vial size

0.4 mL

Storage

Store at 2 - 8°C for up to six months or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

A splice-site mutation in a retina-specific exon of BBS8 causes nonsyndromic retinitis pigmentosa.

Riazuddin SA, Iqbal M, Wang Y, Masuda T, Chen Y, Bowne S, Sullivan LS, Waseem NH, Bhattacharya S, Daiger SP, Zhang K, Khan SN, Riazuddin S, Hejtmancik JF, Sieving PA, Zack DJ, Katsanis N
American journal of human genetics 2010 May 14;86(5):805-12

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A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis.

Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peränen J, Merdes A, Slusarski DC, Scheller RH, Bazan JF, Sheffield VC, Jackson PK
Cell 2007 Jun 15;129(6):1201-13

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Basal body dysfunction is a likely cause of pleiotropic Bardet-Biedl syndrome.

Ansley SJ, Badano JL, Blacque OE, Hill J, Hoskins BE, Leitch CC, Kim JC, Ross AJ, Eichers ER, Teslovich TM, Mah AK, Johnsen RC, Cavender JC, Lewis RA, Leroux MR, Beales PL, Katsanis N
Nature 2003 Oct 9;425(6958):628-33

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB