Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12221-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12221-1-AP, RRID:AB_2063960
- Product name
- BMP7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated BMP7 antibody (Cat. #12221-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Expression Analysis of Early Metastatic Seeding of Colorectal Cancer.
TLR2 regulates hair follicle cycle and regeneration via BMP signaling.
Cell communication pathway prognostic model identified detrimental neurodevelopmental pathways in neuroblastoma.
TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling.
Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity.
Huangqi decoction ameliorates kidney injury in db/db mice by regulating the BMP/Smad signaling pathway.
Omentin-1 drives cardiomyocyte cell cycle arrest and metabolic maturation by interacting with BMP7.
BMP-7 Upregulates Id2 Through the MAPK Signaling Pathway to Improve Diabetic Tubulointerstitial Fibrosis and the Intervention of Oxymatrine.
BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease.
miR-122-5p targets GREM2 to protect against glucocorticoid-induced endothelial damage through the BMP signaling pathway.
LncRNA CRLM1 inhibits apoptosis and promotes metastasis through transcriptional regulation cooperated with hnRNPK in colorectal cancer.
Concentrated small extracellular vesicles from menstrual blood-derived stromal cells improve intrauterine adhesion, a pre-clinical study in a rat model.
Anti‑proliferative effect of honokiol on SW620 cells through upregulating BMP7 expression via the TGF‑β1/p53 signaling pathway.
Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf.
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
A New Insight of Kartogenin Induced the Mesenchymal Stem Cells (MSCs) Selectively Differentiate into Chondrocytes by Activating the Bone Morphogenetic Protein 7 (BMP-7)/Smad5 Pathway.
BMP-7 inhibits renal fibrosis in diabetic nephropathy via miR-21 downregulation.
Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7.
MiR542-3p Regulates the Epithelial-Mesenchymal Transition by Directly Targeting BMP7 in NRK52e.
Prognostic significance of BMP7 as an oncogene in hepatocellular carcinoma.
Sawada A, Ohira M, Hatanaka KC, Matsui H, Ichikawa N, Yoshida T, Fukai M, Matsuno Y, Homma S, Hatanaka Y, Taketomi A
Annals of surgical oncology 2024 Mar;31(3):2101-2113
Annals of surgical oncology 2024 Mar;31(3):2101-2113
TLR2 regulates hair follicle cycle and regeneration via BMP signaling.
Xiong L, Zhevlakova I, West XZ, Gao D, Murtazina R, Horak A, Brown JM, Molokotina I, Podrez EA, Byzova TV
eLife 2024 Mar 14;12
eLife 2024 Mar 14;12
Cell communication pathway prognostic model identified detrimental neurodevelopmental pathways in neuroblastoma.
Wang J, Li H, Xue Y, Zhang Y, Ma X, Zhou C, Rong L, Zhang Y, Wang Y, Fang Y
Neoplasia (New York, N.Y.) 2024 Jun;52:100997
Neoplasia (New York, N.Y.) 2024 Jun;52:100997
TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling.
Xiong L, Zhevlakova I, West XZ, Gao D, Murtazina R, Horak A, Brown JM, Molokotina I, Podrez EA, Byzova TV
bioRxiv : the preprint server for biology 2023 Sep 20;
bioRxiv : the preprint server for biology 2023 Sep 20;
Systematic in vivo candidate evaluation uncovers therapeutic targets for LMNA dilated cardiomyopathy and risk of Lamin A toxicity.
Tan CY, Chan PS, Tan H, Tan SW, Lee CJM, Wang JW, Ye S, Werner H, Loh YJ, Lee YL, Ackers-Johnson M, Foo RSY, Jiang J
Journal of translational medicine 2023 Oct 16;21(1):690
Journal of translational medicine 2023 Oct 16;21(1):690
Huangqi decoction ameliorates kidney injury in db/db mice by regulating the BMP/Smad signaling pathway.
Chen Y, Rui R, Wang L, Wang H, Zhu B, Cao A
BMC complementary medicine and therapies 2023 Jun 26;23(1):209
BMC complementary medicine and therapies 2023 Jun 26;23(1):209
Omentin-1 drives cardiomyocyte cell cycle arrest and metabolic maturation by interacting with BMP7.
Yang H, Song S, Li J, Li Y, Feng J, Sun Q, Qiu X, Chen Z, Bai X, Liu X, Lian H, Liu L, Bai Y, Zhang G, Nie Y
Cellular and molecular life sciences : CMLS 2023 Jun 21;80(7):186
Cellular and molecular life sciences : CMLS 2023 Jun 21;80(7):186
BMP-7 Upregulates Id2 Through the MAPK Signaling Pathway to Improve Diabetic Tubulointerstitial Fibrosis and the Intervention of Oxymatrine.
Xiao Y, Liang D, Li Z, Feng Z, Yuan Z, Zhang F, Wang Y, Zhou Y, Shi M, Liu L, Xiao Y, Guo B
Frontiers in pharmacology 2022;13:900346
Frontiers in pharmacology 2022;13:900346
BMP-7 ameliorates partial epithelial-mesenchymal transition by restoring SnoN protein level via Smad1/5 pathway in diabetic kidney disease.
Peng W, Zhou X, Xu T, Mao Y, Zhang X, Liu H, Liang L, Liu L, Liu L, Xiao Y, Zhang F, Li S, Shi M, Zhou Y, Tang L, Wang Y, Guo B
Cell death & disease 2022 Mar 21;13(3):254
Cell death & disease 2022 Mar 21;13(3):254
miR-122-5p targets GREM2 to protect against glucocorticoid-induced endothelial damage through the BMP signaling pathway.
Huang X, Jie S, Li W, Li H, Ni J, Liu C
Molecular and cellular endocrinology 2022 Mar 15;544:111541
Molecular and cellular endocrinology 2022 Mar 15;544:111541
LncRNA CRLM1 inhibits apoptosis and promotes metastasis through transcriptional regulation cooperated with hnRNPK in colorectal cancer.
Wang Z, Chen J, Sun F, Zhao X, Dong Y, Yu S, Li J, Liang H
Cell & bioscience 2022 Jul 30;12(1):120
Cell & bioscience 2022 Jul 30;12(1):120
Concentrated small extracellular vesicles from menstrual blood-derived stromal cells improve intrauterine adhesion, a pre-clinical study in a rat model.
Zhang S, Chang Q, Li P, Tong X, Feng Y, Hao X, Zhang X, Yuan Z, Tan J
Nanoscale 2021 Apr 21;13(15):7334-7347
Nanoscale 2021 Apr 21;13(15):7334-7347
Anti‑proliferative effect of honokiol on SW620 cells through upregulating BMP7 expression via the TGF‑β1/p53 signaling pathway.
Li Q, Ma Y, Liu XL, Mu L, He BC, Wu K, Sun WJ
Oncology reports 2020 Nov;44(5):2093-2107
Oncology reports 2020 Nov;44(5):2093-2107
Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf.
Tan CY, Wong JX, Chan PS, Tan H, Liao D, Chen W, Tan LW, Ackers-Johnson M, Wakimoto H, Seidman JG, Seidman CE, Lunde IG, Zhu F, Hu Q, Bian J, Wang JW, Foo RS, Jiang J
Circulation research 2019 Oct 11;125(9):834-846
Circulation research 2019 Oct 11;125(9):834-846
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
Wang M, Xiong L, Jiang LJ, Lu YZ, Liu F, Song LJ, Xiang F, He XL, Yu F, Shuai SY, Ma WL, Ye H
EBioMedicine 2019 Mar;41:670-682
EBioMedicine 2019 Mar;41:670-682
A New Insight of Kartogenin Induced the Mesenchymal Stem Cells (MSCs) Selectively Differentiate into Chondrocytes by Activating the Bone Morphogenetic Protein 7 (BMP-7)/Smad5 Pathway.
Zhou Q, Zhang JH, Yuan S, Shao JH, Cai ZY, Chen S, Cao J, Wu HS, Qian QR
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 4;25:4960-4967
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 4;25:4960-4967
BMP-7 inhibits renal fibrosis in diabetic nephropathy via miR-21 downregulation.
Liu L, Wang Y, Yan R, Liang L, Zhou X, Liu H, Zhang X, Mao Y, Peng W, Xiao Y, Zhang F, Liu L, Shi M, Guo B
Life sciences 2019 Dec 1;238:116957
Life sciences 2019 Dec 1;238:116957
Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7.
Chen T, Wu Q, Zhang Y, Lu T, Yue W, Zhang D
Frontiers in molecular neuroscience 2016;9:94
Frontiers in molecular neuroscience 2016;9:94
MiR542-3p Regulates the Epithelial-Mesenchymal Transition by Directly Targeting BMP7 in NRK52e.
Liu Z, Zhou Y, Yuan Y, Nie F, Peng R, Li Q, Lyu Z, Mao Z, Huang L, Zhou L, Li Y, Hao J, Ni D, Jin Q, Long Y, Ju P, Yu W, Liu J, Hu Y, Zhou Q
International journal of molecular sciences 2015 Nov 24;16(11):27945-55
International journal of molecular sciences 2015 Nov 24;16(11):27945-55
Prognostic significance of BMP7 as an oncogene in hepatocellular carcinoma.
Li W, Cai HX, Ge XM, Li K, Xu WD, Shi WH
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013 Apr;34(2):669-74
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2013 Apr;34(2):669-74
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 12221-1-AP( BMP7 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The BMP7 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human BMP7. This antibody recognizes human,mouse,rat antigen. The BMP7 antibody has been validated for the following applications: ELISA, WB, IHC analysis.