BS6661

antibody from Bioworld Technology, Inc
Targeting: MCM6 Mis5
Provider product page for BS6661
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS6661 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MCM6 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MCM6.
Description
The mini-chromosome maintenance (MCM) family of proteins, including MCM2, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle. The MCM proteins each contain an ATP-binding motif, which is predicted to mediate ATP-dependent opening of double-stranded DNA. MCM proteins are regulated by E2F transcription factors, which induce MCM expression, and by protein kinases, which interact with MCM proteins to maintain the postreplicative state of the cell. MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro. Cleavage of MCM3, which can be prevented by caspase inhibitors, results in the inactivation during apoptosis of the MCM complex, which is composed of, at least, MCM2ÿ6.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MCM6 protein structure - BS6661 shown in red.