Antibody data

Product number
Ab122143 - Provider product page
Provider
Aladdin Scientific
Product name
PKM Antibody
Antibody type
Polyclonal
Description
Rabbit anti Human PKM Antibody, Polyclonal, could be used for WB, IHC, ICC/IF and so on.ApplicationWB: 0.01-2 µg/mLIHC: 5-20 µg/mLICC/IF: 5-20 _g/mLProtein FunctionGlycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
AA 141-248
Vial size
100_l,10_l,1ml,20_l,50_l
Concentration
Lot by Lot
Storage
Store at 4_ short term (1-2 weeks). Store at -20_ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
PKM protein structure - Ab122143 shown in red.