abx001594

antibody from Abbexa

Targeting: UBE2D1 E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

abx001594

Provider

Abbexa

Product name

Ubiquitin-Conjugating Enzyme E2 D1 (UBE2D1) Antibody

Antibody type

Polyclonal

Description

UBE2D1 Antibody is a Rabbit Polyclonal antibody against UBE2D1. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

1.37 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.