Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PAB8748 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB8748, RRID:AB_1675230
- Product name
- HDAC10 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of HDAC10.
- Storage
- Store at -20°C. For long term storage store at -80°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells.
Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.
Fiskus W, Rao R, Fernandez P, Herger B, Yang Y, Chen J, Kolhe R, Mandawat A, Wang Y, Joshi R, Eaton K, Lee P, Atadja P, Peiper S, Bhalla K
Blood 2008 Oct 1;112(7):2896-905
Blood 2008 Oct 1;112(7):2896-905
Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.
Bali P, Pranpat M, Bradner J, Balasis M, Fiskus W, Guo F, Rocha K, Kumaraswamy S, Boyapalle S, Atadja P, Seto E, Bhalla K
The Journal of biological chemistry 2005 Jul 22;280(29):26729-34
The Journal of biological chemistry 2005 Jul 22;280(29):26729-34
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of HDAC10 expression. Lane 1: Jurkat Cells, Lane 2: Mouse Intestine, Lane 3: Rat Brain. The antibody recognizes 74 kDa HDAC-10 of human, mouse, and rat origins. 55 kDa cleavage fragment can also be detected in mouse and rat tissue lysates.