11-4021

antibody from ABEOMICS Inc.
Targeting: NR2F6 EAR-2, EAR2, ERBAL2
Provider product page for 11-4021

Antibody data

Product number
11-4021 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-NR2F6 Antibody
Antibody type
Polyclonal
Description
NR2F6 (Nuclear receptor subfamily 2 group F member 6) is a nuclear zinc-finger orphan receptor which acts as a critical PKC (protein kinase C) substrate and essential regulator of CD4(+) T cell activation responses. It Inhibits NFATC (Nuclear factor of activated T-cells) transcription factor DNA binding and subsequently its transcriptional activity. It acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4+ T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. It is involved in development of forebrain circadian clock.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant NR2F6
protein (amino acids 210-400) was u
sed as the immunogen for this antib
ody.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
NR2F6 protein structure - 11-4021 shown in red.