AMM03446G

antibody from Leading Biology

Targeting: CYP46A1 CYP46

Western blot (Recommended by provider)

Antibody Data

Product number

AMM03446G

Provider

Leading Biology

Product name

CYP46A1 Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

1A11

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.