Explore
Validate
Learn
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [3]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NB400-140 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB400-140, RRID:AB_10146511
- Product name
- Rabbit Polyclonal CYP46A1 Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified.
- Reactivity
- Human, Mouse, Rabbit
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Glutamate affects cholesterol homeostasis within the brain via the up-regulation of CYP46A1 and ApoE.
Differential expression of cholesterol hydroxylases in Alzheimer's disease.
Zhang J, Zhang F, Wu J, Li J, Yang Z, Yue J
Toxicology 2020 Feb 28;432:152381
Toxicology 2020 Feb 28;432:152381
Differential expression of cholesterol hydroxylases in Alzheimer's disease.
Brown J 3rd, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B
The Journal of biological chemistry 2004 Aug 13;279(33):34674-81
The Journal of biological chemistry 2004 Aug 13;279(33):34674-81
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CYP46A1 Antibody [NB400-140] - Blocking experiment using NB 400-140 in HEK293 cells overexpressing CYP46A1.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CYP46A1 Antibody [NB400-140] - Analysis of Cyp-46 in HEK293 cells overexpressing CYP46A1 or transfected with an empty vector using NB400-140.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CYP46A1 Antibody [NB400-140] - Detection of Cyp46 in human brain lysates.
