602302

antibody from BioLegend

Targeting: MCM3

Western blot (Data presented on provider website)

Antibody Data

Product number

602302

Provider

BioLegend

Proper citation

BioLegend Cat#602302, RRID:AB_2142256

Product name

Purified anti-MCM3

Antibody type

Polyclonal

Antigen

Peptide

Description

The MCM3 protein (minichromosome maintenance protein 3) is a 110 kD DNA-dependent ATPase containing a nuclear localization sequence. The MCM3 protein is a component of the DNA pre-replication complex that acts to allow DNA to undergo single round of replication per cell cycle. MCM3 is constitutively expressed and can be modified by acetylation. Acetylation of MCM3 inhibits the initiation of DNA replication. MCM3 has been reported to interact with the MCM5 (CDC46) and MCM3AP proteins. The Poly6023 antibody recognizes both human and mouse MCM3 and has been shown to be useful for Western blotting.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Vial size

200 µl

Storage

Upon receipt, store frozen at -20° C.

References

Submitted references

Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation.

Yim H, Erikson RL
Molecular and cellular biology 2009 May;29(10):2609-21