BS7922

antibody from Bioworld Technology, Inc

Targeting: CSF2 GM-CSF, GMCSF

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS7922

Provider

Bioworld Technology, Inc

Product name

CSF2 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human CSF2.

Description

?Colony stimulating factors (CSFs) were initially characterized by their ability to stimulate in vitro colony formation by hematopoietic progenitor cells in semisolid media. Several of these CSFs have been assigned an interleukin number, while three (GM-CSF, G-CSF and M-CSF) have retained their CSF designations. The human granulocyte-macrophage colony stimulating factor (GM-CSF) is a pleiotropic cytokine with a 17 amino acid signal peptide that is cleaved to produce the mature form of 127 amino acids. The mature murine GM-CSF protein is 124 amino acids and shares 60% homology with the human GM-CSF protein. GM-CSF is a glycoprotein that can stimulate the proliferation of hematopoietic cells including granulocytes and macrophages. It has been shown to promote the phosphorylation of cPLA2 in human neutrophils. The phosphorylation of cPLA2 may be accompanied by an increase in enzyme activity.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.