BS6790

antibody from Bioworld Technology, Inc
Targeting: COPS5 CSN5, JAB1, MOV-34, SGN5
Provider product page for BS6790
Western blot
Immunohistochemistry

Antibody data

Product number
BS6790 - Provider product page
Provider
Bioworld Technology, Inc
Product name
COPS5 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human COPS5.
Description
Genes belonging to the Jun and Fos oncogene families encode nuclear proteins that are found to be associated with a number of transcriptional complexes. The c-Jun protein is a major component of the transcription factor AP-1, originally shown to mediate phorbol ester tumor promoter (TPA)-induced expression of responsive genes through the TPA-response element (TRE). The Jun proteins form homo- and heterodimers which bind the TRE, but the Fos proteins are active only as heterodimers with any of the Jun proteins. Fos/Jun heterodimers have a much higher affinity for the TRE than Jun homodimers. Ha-Ras augments c-Jun activity and stimulates phosphorylation of its activation domain. The coactivator of Jun, designated JAB1 (for Jun-activation domain-binding protein), interacts with c-Jun and Jun D, but not with Jun B or v-Jun. This interaction enhances the transactivating ability of Jun proteins by stabilizing their binding to the TRE.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
COPS5 protein structure - BS6790 shown in red.