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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [3]
- Immunohistochemistry [1]
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- Product number
- NB120-495 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB120-495, RRID:AB_1145965
- Product name
- Mouse Monoclonal JAB1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified.
- Reactivity
- Human, Mouse, Rat, Drosophila
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 ul
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Nedd8 hydrolysis by UCH proteases in Plasmodium parasites.
COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain.
COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).
Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development.
Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5.
CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint.
The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway.
Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors.
Karpiyevich M, Adjalley S, Mol M, Ascher DB, Mason B, van der Heden van Noort GJ, Laman H, Ovaa H, Lee MCS, Artavanis-Tsakonas K
PLoS pathogens 2019 Oct;15(10):e1008086
PLoS pathogens 2019 Oct;15(10):e1008086
COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain.
Wang R, Wang H, Carrera I, Xu S, Lakshmana MK
The Journal of biological chemistry 2015 Apr 3;290(14):9299-309
The Journal of biological chemistry 2015 Apr 3;290(14):9299-309
COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.
Wang H, Dey D, Carrera I, Minond D, Bianchi E, Xu S, Lakshmana MK
The Journal of biological chemistry 2013 Sep 13;288(37):26668-77
The Journal of biological chemistry 2013 Sep 13;288(37):26668-77
The D-dopachrome tautomerase (DDT) gene product is a cytokine and functional homolog of macrophage migration inhibitory factor (MIF).
Merk M, Zierow S, Leng L, Das R, Du X, Schulte W, Fan J, Lue H, Chen Y, Xiong H, Chagnon F, Bernhagen J, Lolis E, Mor G, Lesur O, Bucala R
Proceedings of the National Academy of Sciences of the United States of America 2011 Aug 23;108(34):E577-85
Proceedings of the National Academy of Sciences of the United States of America 2011 Aug 23;108(34):E577-85
Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development.
McCall CM, Miliani de Marval PL, Chastain PD 2nd, Jackson SC, He YJ, Kotake Y, Cook JG, Xiong Y
Molecular and cellular biology 2008 Sep;28(18):5621-33
Molecular and cellular biology 2008 Sep;28(18):5621-33
Interaction between glucose-regulated destruction domain of DNA topoisomerase IIalpha and MPN domain of Jab1/CSN5.
Yun J, Tomida A, Andoh T, Tsuruo T
The Journal of biological chemistry 2004 Jul 23;279(30):31296-303
The Journal of biological chemistry 2004 Jul 23;279(30):31296-303
CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint.
Doronkin S, Djagaeva I, Beckendorf SK
Development (Cambridge, England) 2002 Nov;129(21):5053-64
Development (Cambridge, England) 2002 Nov;129(21):5053-64
The TRC8 hereditary kidney cancer gene suppresses growth and functions with VHL in a common pathway.
Gemmill RM, Bemis LT, Lee JP, Sozen MA, Baron A, Zeng C, Erickson PF, Hooper JE, Drabkin HA
Oncogene 2002 May 16;21(22):3507-16
Oncogene 2002 May 16;21(22):3507-16
Expression of phosphorylated p27(Kip1) protein and Jun activation domain-binding protein 1 in human pituitary tumors.
Korbonits M, Chahal HS, Kaltsas G, Jordan S, Urmanova Y, Khalimova Z, Harris PE, Farrell WE, Claret FX, Grossman AB
The Journal of clinical endocrinology and metabolism 2002 Jun;87(6):2635-43
The Journal of clinical endocrinology and metabolism 2002 Jun;87(6):2635-43
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: JAB1 Antibody (2A10) [NB120-495] - Jab1 antibody [2A10.8] Sample (50 ug of whole cell lysate) A: mouse brain 10% SDS PAGE JAB1 Antibody diluted at 1:10000
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: JAB1 Antibody (2A10) [NB120-495] - Jab1 antibody detects Jab1 protein by western blot analysis. Various whole cell extracts (30 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with Jab1 antibody diluted at a dilution of 1:500.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: JAB1 Antibody (2A10) [NB120-495] - Sample (50 ug of whole cell lysate) A: Rat liver 10% SDS PAGE diluted at 1:1000
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: JAB1 Antibody (2A10) [NB120-495]
