Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11650-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11650-2-AP, RRID:AB_2071136
- Product name
- CBX3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CBX3 antibody (Cat. #11650-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Prognostic and immune infiltrates for the Chromobox (CBX) protein family in human pancreatic adenocarcinoma.
Smoking-associated upregulation of CBX3 suppresses ARHGAP24 expression to activate Rac1 signaling and promote tumor progression in lung adenocarcinoma.
PCA3 controls chromatin organization and p53 signal activation by regulating LAP2α-lamin A complexes.
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
PIWIL4 Maintains HIV-1 Latency by Enforcing Epigenetically Suppressive Modifications on the 5' Long Terminal Repeat.
ZNF143-Mediated H3K9 Trimethylation Upregulates CDC6 by Activating MDIG in Hepatocellular Carcinoma.
CBX3/HP1γ promotes tumor proliferation and predicts poor survival in hepatocellular carcinoma.
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
CBX3 promotes tumor proliferation by regulating G1/S phase via p21 downregulation and associates with poor prognosis in tongue squamous cell carcinoma.
A pH probe inhibits senescence in mesenchymal stem cells.
The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction.
RNA sequencing identifies novel markers of non-small cell lung cancer.
Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins.
Li Q, Fu L, Wu D, Wang J
Journal of gastrointestinal oncology 2021 Oct;12(5):2310-2324
Journal of gastrointestinal oncology 2021 Oct;12(5):2310-2324
Smoking-associated upregulation of CBX3 suppresses ARHGAP24 expression to activate Rac1 signaling and promote tumor progression in lung adenocarcinoma.
Jin X, Zhang B, Zhang H, Yu H
Oncogene 2021 Nov 16;
Oncogene 2021 Nov 16;
PCA3 controls chromatin organization and p53 signal activation by regulating LAP2α-lamin A complexes.
Ito S, Ueda T, Yokoyama A, Fujihara A, Hongo F, Ukimura O
Cancer gene therapy 2021 Mar 23;
Cancer gene therapy 2021 Mar 23;
The LncRNA RP11-279C4.1 Enhances the Malignant Behaviour of Glioma Cells and Glioma Stem-Like Cells by Regulating the miR-1273g-3p/CBX3 Axis.
Wang F, Zhang L, Luo Y, Zhang Q, Zhang Y, Shao Y, Yuan L
Molecular neurobiology 2021 Jul;58(7):3362-3373
Molecular neurobiology 2021 Jul;58(7):3362-3373
ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.
Ma L, Yu L, Jiang BC, Wang J, Guo X, Huang Y, Ren J, Sun N, Gao DS, Ding H, Lu J, Zhou H, Zou L, Gao Y, Wang L, Sun K, Ming Y, Meng Z, Tao YX, Yan M
The Journal of experimental medicine 2021 Dec 6;218(12)
The Journal of experimental medicine 2021 Dec 6;218(12)
PIWIL4 Maintains HIV-1 Latency by Enforcing Epigenetically Suppressive Modifications on the 5' Long Terminal Repeat.
He Z, Jing S, Yang T, Chen J, Huang F, Zhang W, Peng Z, Liu B, Ma X, Wu L, Pan T, Zhang X, Li L, Cai W, Tang X, Zhang J, Zhang H
Journal of virology 2020 May 4;94(10)
Journal of virology 2020 May 4;94(10)
ZNF143-Mediated H3K9 Trimethylation Upregulates CDC6 by Activating MDIG in Hepatocellular Carcinoma.
Zhang L, Huo Q, Ge C, Zhao F, Zhou Q, Chen X, Tian H, Chen T, Xie H, Cui Y, Yao M, Li H, Li J
Cancer research 2020 Jun 15;80(12):2599-2611
Cancer research 2020 Jun 15;80(12):2599-2611
CBX3/HP1γ promotes tumor proliferation and predicts poor survival in hepatocellular carcinoma.
Zhong X, Kan A, Zhang W, Zhou J, Zhang H, Chen J, Tang S
Aging 2019 Aug 2;11(15):5483-5497
Aging 2019 Aug 2;11(15):5483-5497
Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors.
Huang X, Yan J, Zhang M, Wang Y, Chen Y, Fu X, Wei R, Zheng XL, Liu Z, Zhang X, Yang H, Hao B, Shen YY, Su Y, Cong X, Huang M, Tan M, Ding J, Geng M
Cell 2018 Sep 20;175(1):186-199.e19
Cell 2018 Sep 20;175(1):186-199.e19
CBX3 promotes tumor proliferation by regulating G1/S phase via p21 downregulation and associates with poor prognosis in tongue squamous cell carcinoma.
Zhang H, Chen W, Fu X, Su X, Yang A
Gene 2018 May 15;654:49-56
Gene 2018 May 15;654:49-56
A pH probe inhibits senescence in mesenchymal stem cells.
Wang L, Han X, Qu G, Su L, Zhao B, Miao J
Stem cell research & therapy 2018 Dec 7;9(1):343
Stem cell research & therapy 2018 Dec 7;9(1):343
The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction.
Yang G, Weng X, Zhao Y, Zhang X, Hu Y, Dai X, Liang P, Wang P, Ma L, Sun X, Hou L, Xu H, Fang M, Li Y, Jenuwein T, Xu Y, Sun A
Nature communications 2017 Mar 31;8:14941
Nature communications 2017 Mar 31;8:14941
RNA sequencing identifies novel markers of non-small cell lung cancer.
Han SS, Kim WJ, Hong Y, Hong SH, Lee SJ, Ryu DR, Lee W, Cho YH, Lee S, Ryu YJ, Won JY, Rhee H, Park JH, Jang SJ, Lee JS, Choi CM, Lee JC, Lee SD, Oh YM
Lung cancer (Amsterdam, Netherlands) 2014 Jun;84(3):229-35
Lung cancer (Amsterdam, Netherlands) 2014 Jun;84(3):229-35
Induction of alternative lengthening of telomeres-associated PML bodies by p53/p21 requires HP1 proteins.
Jiang WQ, Zhong ZH, Nguyen A, Henson JD, Toouli CD, Braithwaite AW, Reddel RR
The Journal of cell biology 2009 Jun 1;185(5):797-810
The Journal of cell biology 2009 Jun 1;185(5):797-810
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11650-2-AP(CBX3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CBX3 antibody 11650-2-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11650-2-AP(CBX3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue