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- Product number
- ABIN393973 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Filamin Binding LIM Protein 1 (FBLIM1) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 5E11
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Migfilin, a molecular switch in regulation of integrin activation.
Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling.
Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome.
Structural basis of the migfilin-filamin interaction and competition with integrin beta tails.
Increased cytoplasmic level of migfilin is associated with higher grades of human leiomyosarcoma.
Ithychanda SS, Das M, Ma YQ, Ding K, Wang X, Gupta S, Wu C, Plow EF, Qin J
The Journal of biological chemistry 2009 Feb 13;284(7):4713-22
The Journal of biological chemistry 2009 Feb 13;284(7):4713-22
Migfilin interacts with Src and contributes to cell-matrix adhesion-mediated survival signaling.
Zhao J, Zhang Y, Ithychanda SS, Tu Y, Chen K, Qin J, Wu C
The Journal of biological chemistry 2009 Dec 4;284(49):34308-20
The Journal of biological chemistry 2009 Dec 4;284(49):34308-20
Colocalization of kindlin-1, kindlin-2, and migfilin at keratinocyte focal adhesion and relevance to the pathophysiology of Kindler syndrome.
Lai-Cheong JE, Ussar S, Arita K, Hart IR, McGrath JA
The Journal of investigative dermatology 2008 Sep;128(9):2156-65
The Journal of investigative dermatology 2008 Sep;128(9):2156-65
Structural basis of the migfilin-filamin interaction and competition with integrin beta tails.
Lad Y, Jiang P, Ruskamo S, Harburger DS, Ylänne J, Campbell ID, Calderwood DA
The Journal of biological chemistry 2008 Dec 12;283(50):35154-63
The Journal of biological chemistry 2008 Dec 12;283(50):35154-63
Increased cytoplasmic level of migfilin is associated with higher grades of human leiomyosarcoma.
Papachristou DJ, Gkretsi V, Tu Y, Shi X, Chen K, Larjava H, Rao UN, Wu C
Histopathology 2007 Oct;51(4):499-508
Histopathology 2007 Oct;51(4):499-508
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- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
