BS1144

antibody from Bioworld Technology, Inc

Targeting: GRM4 GPRC1D, mGlu4, MGLUR4

Immunohistochemistry

Antibody data

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Validation data

Product number: BS1144 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS1144, RRID:AB_1662880
Product name: mGluR 4 (Q875) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 840-893 of Human mGluR-4.
Description: The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-4,which can interact with PRKCABP, acts as a receptor for glutamate. It is highly expressed in cerebellum.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

GRM4 protein structure - BS1144 shown in red.