Tissue expression
Cell line expression
Protein structure
ACVR1B
Activin A receptor type 1BActRIB, ACVRLK4, ALK4, SKR2
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Top validated antibodies |
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| Abnova Corporation | 1 references | Monoclonal |
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| Proteintech Group | 7 references | Polyclonal |
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| R&D Systems | 1 references | Polyclonal |
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| Novus Biologicals | 1 references | Polyclonal |
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| LSBio | Polyclonal |
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