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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- PAB12052 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12052, RRID:AB_1712457
- Product name
- RAD50 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against partial recombinant RAD50.
- Storage
- Store at 4°C for short term. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Dimerization of the Rad50 protein is independent of the conserved hook domain.
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair.
The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response.
Cahill D, Carney JP
Mutagenesis 2007 Jul;22(4):269-74
Mutagenesis 2007 Jul;22(4):269-74
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair.
Hopfner KP, Craig L, Moncalian G, Zinkel RA, Usui T, Owen BA, Karcher A, Henderson B, Bodmer JL, McMurray CT, Carney JP, Petrini JH, Tainer JA
Nature 2002 Aug 1;418(6897):562-6
Nature 2002 Aug 1;418(6897):562-6
The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response.
Petrini JH
American journal of human genetics 1999 May;64(5):1264-9
American journal of human genetics 1999 May;64(5):1264-9
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of RAD50 in 25 ng purified hMre11-hRAD50 complex (Lane 1) and 25 ug crude HeLa extract (Lane 2 :) with RAD50 polyclonal antibody (Cat # PAB12052).
