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Learn12235-1-AP
antibody from Proteintech Group
Targeting: NR4A1
GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 12235-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12235-1-AP, RRID:AB_10644125
- Product name
- NR4A1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NR4A1 antibody (Cat. #12235-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change.
A systematic dissection of human primary osteoblasts in vivo at single-cell resolution.
Simvastatin Improves Behavioral Disorders and Hippocampal Inflammatory Reaction by NMDA-Mediated Anti-inflammatory Function in MPTP-Treated Mice.
Ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 inhibits inflammation by regulating Nur77 stability.
The E3 ubiquitin ligase Trim13 regulates Nur77 stability via casein kinase 2α.
Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress.
Contra-directional Coupling of Nur77 and Nurr1 in Neurodegeneration: A Novel Mechanism for Memantine-Induced Anti-inflammation and Anti-mitochondrial Impairment.
NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B.
Antitumor activity of SAHA, a novel histone deacetylase inhibitor, against murine B cell lymphoma A20 cells in vitro and in vivo.
The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.
Payapilly A, Guilbert R, Descamps T, White G, Magee P, Zhou C, Kerr A, Simpson KL, Blackhall F, Dive C, Malliri A
Cell reports 2021 Nov 9;37(6):109979
Cell reports 2021 Nov 9;37(6):109979
A systematic dissection of human primary osteoblasts in vivo at single-cell resolution.
Gong Y, Yang J, Li X, Zhou C, Chen Y, Wang Z, Qiu X, Liu Y, Zhang H, Greenbaum J, Cheng L, Hu Y, Xie J, Yang X, Li Y, Bai Y, Wang YP, Chen Y, Tan LJ, Shen H, Xiao HM, Deng HW
Aging 2021 Aug 24;13(16):20629-20650
Aging 2021 Aug 24;13(16):20629-20650
Simvastatin Improves Behavioral Disorders and Hippocampal Inflammatory Reaction by NMDA-Mediated Anti-inflammatory Function in MPTP-Treated Mice.
Yan J, Liu A, Fan H, Qiao L, Wu J, Shen M, Lai X, Huang J
Cellular and molecular neurobiology 2020 Oct;40(7):1155-1164
Cellular and molecular neurobiology 2020 Oct;40(7):1155-1164
Ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 inhibits inflammation by regulating Nur77 stability.
Pei HZ, Huang B, Chang HW, Baek SH
Cellular signalling 2019 Jul;59:85-95
Cellular signalling 2019 Jul;59:85-95
The E3 ubiquitin ligase Trim13 regulates Nur77 stability via casein kinase 2α.
Huang B, Pei HZ, Chang HW, Baek SH
Scientific reports 2018 Sep 17;8(1):13895
Scientific reports 2018 Sep 17;8(1):13895
Nur77 exacerbates PC12 cellular injury in vitro by aggravating mitochondrial impairment and endoplasmic reticulum stress.
Gao H, Chen Z, Fu Y, Yang X, Weng R, Wang R, Lu J, Pan M, Jin K, McElroy C, Tang B, Xia Y, Wang Q
Scientific reports 2016 Sep 29;6:34403
Scientific reports 2016 Sep 29;6:34403
Contra-directional Coupling of Nur77 and Nurr1 in Neurodegeneration: A Novel Mechanism for Memantine-Induced Anti-inflammation and Anti-mitochondrial Impairment.
Wei X, Gao H, Zou J, Liu X, Chen D, Liao J, Xu Y, Ma L, Tang B, Zhang Z, Cai X, Jin K, Xia Y, Wang Q
Molecular neurobiology 2016 Nov;53(9):5876-5892
Molecular neurobiology 2016 Nov;53(9):5876-5892
NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B.
Zhang Y, Chen G, Gao B, Li Y, Liang S, Wang X, Wang X, Zhu B
Scientific reports 2016 Nov 23;6:37713
Scientific reports 2016 Nov 23;6:37713
Antitumor activity of SAHA, a novel histone deacetylase inhibitor, against murine B cell lymphoma A20 cells in vitro and in vivo.
Yang B, Yu D, Liu J, Yang K, Wu G, Liu H
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Jul;36(7):5051-61
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015 Jul;36(7):5051-61
The Orphan Nuclear Receptor NR4A1 Protects Pancreatic β-Cells from Endoplasmic Reticulum (ER) Stress-mediated Apoptosis.
Yu C, Cui S, Zong C, Gao W, Xu T, Gao P, Chen J, Qin D, Guan Q, Liu Y, Fu Y, Li X, Wang X
The Journal of biological chemistry 2015 Aug 21;290(34):20687-20699
The Journal of biological chemistry 2015 Aug 21;290(34):20687-20699
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NUR77 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NUR77. This antibody recognizes human,mouse,rat antigen. The NUR77 antibody has been validated for the following applications: ELISA, WB analysis.
