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antibody from antibodies-online
Targeting: NR4A1
GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3
Western blot
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ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- ABIN252681 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (AA 251-266) antibody
- Antibody type
- Polyclonal
- Description
- Protein G purified
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 251-266
- Vial size
- 0.1 mg
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
- Handling
- Avoid freeze-thaw cycles
Submitted references The autism-related gene SNRPN regulates cortical and spine development via controlling nuclear receptor Nr4a1.
Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3'-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells.
Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors.
Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.
Activation of nerve growth factor-induced B alpha by methylene-substituted diindolylmethanes in bladder cancer cells induces apoptosis and inhibits tumor growth.
Different changes in protein and phosphoprotein levels result from serum starvation of high-grade glioma and adenocarcinoma cell lines.
Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77.
p21 expression is induced by activation of nuclear nerve growth factor-induced Balpha (Nur77) in pancreatic cancer cells.
Resistance of Foxp3+ regulatory T cells to Nur77-induced apoptosis promotes allograft survival.
1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.
Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways.
A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily.
Li H, Zhao P, Xu Q, Shan S, Hu C, Qiu Z, Xu X
Scientific reports 2016 Jul 19;6:29878
Scientific reports 2016 Jul 19;6:29878
Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3'-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells.
Li X, Lee SO, Safe S
Biochemical pharmacology 2012 May 15;83(10):1445-55
Biochemical pharmacology 2012 May 15;83(10):1445-55
Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors.
Yoon K, Lee SO, Cho SD, Kim K, Khan S, Safe S
Carcinogenesis 2011 Jun;32(6):836-42
Carcinogenesis 2011 Jun;32(6):836-42
Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.
Lee SO, Abdelrahim M, Yoon K, Chintharlapalli S, Papineni S, Kim K, Wang H, Safe S
Cancer research 2010 Sep 1;70(17):6824-36
Cancer research 2010 Sep 1;70(17):6824-36
Activation of nerve growth factor-induced B alpha by methylene-substituted diindolylmethanes in bladder cancer cells induces apoptosis and inhibits tumor growth.
Cho SD, Lee SO, Chintharlapalli S, Abdelrahim M, Khan S, Yoon K, Kamat AM, Safe S
Molecular pharmacology 2010 Mar;77(3):396-404
Molecular pharmacology 2010 Mar;77(3):396-404
Different changes in protein and phosphoprotein levels result from serum starvation of high-grade glioma and adenocarcinoma cell lines.
Levin VA, Panchabhai SC, Shen L, Kornblau SM, Qiu Y, Baggerly KA
Journal of proteome research 2010 Jan;9(1):179-91
Journal of proteome research 2010 Jan;9(1):179-91
Paclitaxel directly binds to Bcl-2 and functionally mimics activity of Nur77.
Ferlini C, Cicchillitti L, Raspaglio G, Bartollino S, Cimitan S, Bertucci C, Mozzetti S, Gallo D, Persico M, Fattorusso C, Campiani G, Scambia G
Cancer research 2009 Sep 1;69(17):6906-14
Cancer research 2009 Sep 1;69(17):6906-14
p21 expression is induced by activation of nuclear nerve growth factor-induced Balpha (Nur77) in pancreatic cancer cells.
Lee SO, Chintharlapalli S, Liu S, Papineni S, Cho SD, Yoon K, Safe S
Molecular cancer research : MCR 2009 Jul;7(7):1169-78
Molecular cancer research : MCR 2009 Jul;7(7):1169-78
Resistance of Foxp3+ regulatory T cells to Nur77-induced apoptosis promotes allograft survival.
Tao R, Hancock WW
PloS one 2008 May 28;3(5):e2321
PloS one 2008 May 28;3(5):e2321
1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth.
Inamoto T, Papineni S, Chintharlapalli S, Cho SD, Safe S, Kamat AM
Molecular cancer therapeutics 2008 Dec;7(12):3825-33
Molecular cancer therapeutics 2008 Dec;7(12):3825-33
Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways.
Chintharlapalli S, Burghardt R, Papineni S, Ramaiah S, Yoon K, Safe S
The Journal of biological chemistry 2005 Jul 1;280(26):24903-14
The Journal of biological chemistry 2005 Jul 1;280(26):24903-14
A human early response gene homologous to murine nur77 and rat NGFI-B, and related to the nuclear receptor superfamily.
Nakai A, Kartha S, Sakurai A, Toback FG, DeGroot LJ
Molecular endocrinology (Baltimore, Md.) 1990 Oct;4(10):1438-43
Molecular endocrinology (Baltimore, Md.) 1990 Oct;4(10):1438-43
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- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
