2549

antibody from Cell Signaling Technology, Inc

Targeting: CDK9 C-2k, CDC2L4, PITALRE, TAK

Western blot (Data presented on provider website)

Antibody Data

Product number

2549

Provider

Cell Signaling Technology, Inc

Proper citation

Cell Signaling Technology Cat#2549, RRID:AB_2077300

Product name

Phospho-CDK9 (Thr186) Antibody

Antibody type

Polyclonal

Reactivity

Human, Mouse, Rat, Simian

Host

Rabbit

Storage

-20°C

References

Submitted references

T-loop phosphorylated Cdk9 localizes to nuclear speckle domains which may serve as sites of active P-TEFb function and exchange between the Brd4 and 7SK/HEXIM1 regulatory complexes.

Dow EC, Liu H, Rice AP
Journal of cellular physiology 2010 Jul;224(1):84-93

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Characterization of Cdk9 T-loop phosphorylation in resting and activated CD4(+) T lymphocytes.

Ramakrishnan R, Dow EC, Rice AP
Journal of leukocyte biology 2009 Dec;86(6):1345-50

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Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop.

Wang Y, Dow EC, Liang YY, Ramakrishnan R, Liu H, Sung TL, Lin X, Rice AP
The Journal of biological chemistry 2008 Nov 28;283(48):33578-84