CABT-L1236

antibody from Creative Diagnostics

Targeting: CDK9 C-2k, CDC2L4, PITALRE, TAK

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-L1236

Provider

Creative Diagnostics

Product name

Rabbit Anti-Human CDK9 monoclonal antibody, clone L.624.2

Antibody type

Monoclonal

Description

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Reactivity

Human, Mouse, Rat, Bovine, Canine, Hamster

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

L.624.2

Storage

-20°C