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- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 12770-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12770-1-AP, RRID:AB_2117318
- Product name
- HNRNPD antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HNRNPD antibody (Cat. #12770-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Characterization of the protein expression and localization of hnRNP family members during murine spermatogenesis.
Targeting lncRNA DDIT4-AS1 Sensitizes Triple Negative Breast Cancer to Chemotherapy via Suppressing of Autophagy.
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
10-Hydroxydec-2-Enoic Acid Reduces Hydroxyl Free Radical-Induced Damage to Vascular Smooth Muscle Cells by Rescuing Protein and Energy Metabolism.
The hnRNPK/A1/R/U Complex Regulates Gene Transcription and Translation and is a Favorable Prognostic Biomarker for Human Colorectal Adenocarcinoma.
The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer.
Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer.
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
hnRNPM deficiency leads to cognitive deficits via disrupting synaptic plasticity.
Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates.
A Comparative Quantitative Proteomic Analysis of HCMV-Infected Cells Highlights pUL138 as a Multifunctional Protein.
lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.
Angiotensin II contributes to intratumoral immunosuppressionvia induction of PD-L1 expression in non-small cell lung carcinoma.
Identification and Verification of Two Novel Differentially Expressed Proteins from Non-neoplastic Mucosa and Colorectal Carcinoma Via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry.
Acetylation of Cytidine in mRNA Promotes Translation Efficiency.
Unraveling Molecular Differences of Gastric Cancer by Label-Free Quantitative Proteomics Analysis.
Subcellular quantitative proteomic analysis reveals host proteins involved in human cytomegalovirus infection.
Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions.
Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
Wang XL, Li JM, Yuan SQ
Asian journal of andrology 2023 May-Jun;25(3):314-321
Asian journal of andrology 2023 May-Jun;25(3):314-321
Targeting lncRNA DDIT4-AS1 Sensitizes Triple Negative Breast Cancer to Chemotherapy via Suppressing of Autophagy.
Jiang T, Zhu J, Jiang S, Chen Z, Xu P, Gong R, Zhong C, Cheng Y, Sun X, Yi W, Yang J, Zhou W, Cheng Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2207257
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(17):e2207257
LncRNA BC promotes lung adenocarcinoma progression by modulating IMPAD1 alternative splicing.
Chen QW, Cai QQ, Yang Y, Dong S, Liu YY, Chen ZY, Kang CL, Qi B, Dong YW, Wu W, Zhuang LP, Shen YH, Meng ZQ, Wu XZ
Clinical and translational medicine 2023 Jan;13(1):e1129
Clinical and translational medicine 2023 Jan;13(1):e1129
10-Hydroxydec-2-Enoic Acid Reduces Hydroxyl Free Radical-Induced Damage to Vascular Smooth Muscle Cells by Rescuing Protein and Energy Metabolism.
Fan P, Sha F, Ma C, Wei Q, Zhou Y, Shi J, Fu J, Zhang L, Han B, Li J
Frontiers in nutrition 2022;9:873892
Frontiers in nutrition 2022;9:873892
The hnRNPK/A1/R/U Complex Regulates Gene Transcription and Translation and is a Favorable Prognostic Biomarker for Human Colorectal Adenocarcinoma.
Li Y, Wang H, Wan J, Ma Q, Qi Y, Gu Z
Frontiers in oncology 2022;12:845931
Frontiers in oncology 2022;12:845931
The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer.
Hu H, Zhang H, Xing Y, Zhou Y, Chen J, Li C, Xu J, Guo Y, Wang J, He Q, Liu X, Sheng J, Song E, Wu Y, Huang H
Oncogene 2022 Dec;41(49):5298-5314
Oncogene 2022 Dec;41(49):5298-5314
Effects of ribosomal associated protein hnRNP D in gemcitabine-resistant pancreatic cancer.
Wang C, Huang H
Biochemical and biophysical research communications 2021 Nov 19;579:181-187
Biochemical and biophysical research communications 2021 Nov 19;579:181-187
Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.
Ma Y, Liu S, Gao J, Chen C, Zhang X, Yuan H, Chen Z, Yin X, Sun C, Mao Y, Zhou F, Shao Y, Liu Q, Xu J, Cheng L, Yu D, Li P, Yi P, He J, Geng G, Guo Q, Si Y, Zhao H, Li H, Banes GL, Liu H, Nakamura Y, Kurita R, Huang Y, Wang X, Wang F, Fang G, Engel JD, Shi L, Zhang YE, Yu J
Developmental cell 2021 Feb 22;56(4):478-493.e11
Developmental cell 2021 Feb 22;56(4):478-493.e11
hnRNPM deficiency leads to cognitive deficits via disrupting synaptic plasticity.
Akinyemi AR, Li D, Zhang J, Liu Q
Neuroscience letters 2021 Apr 23;751:135824
Neuroscience letters 2021 Apr 23;751:135824
Enzymatic degradation of RNA causes widespread protein aggregation in cell and tissue lysates.
Aarum J, Cabrera CP, Jones TA, Rajendran S, Adiutori R, Giovannoni G, Barnes MR, Malaspina A, Sheer D
EMBO reports 2020 Oct 5;21(10):e49585
EMBO reports 2020 Oct 5;21(10):e49585
A Comparative Quantitative Proteomic Analysis of HCMV-Infected Cells Highlights pUL138 as a Multifunctional Protein.
Li Y, Shang W, Xiao G, Zhang LK, Zheng C
Molecules (Basel, Switzerland) 2020 May 28;25(11)
Molecules (Basel, Switzerland) 2020 May 28;25(11)
lncRNA RMST Suppressed GBM Cell Mitophagy through Enhancing FUS SUMOylation.
Liu C, Peng Z, Li P, Fu H, Feng J, Zhang Y, Liu T, Liu Y, Liu Q, Liu Q, Li D, Wu M
Molecular therapy. Nucleic acids 2020 Mar 6;19:1198-1208
Molecular therapy. Nucleic acids 2020 Mar 6;19:1198-1208
Angiotensin II contributes to intratumoral immunosuppressionvia induction of PD-L1 expression in non-small cell lung carcinoma.
Yang K, Zhou J, Chen Y, Chen Y, Chen L, Zhang P, Ma L, Jiang Z, Bian J, Yin W
International immunopharmacology 2020 Jul;84:106507
International immunopharmacology 2020 Jul;84:106507
Identification and Verification of Two Novel Differentially Expressed Proteins from Non-neoplastic Mucosa and Colorectal Carcinoma Via iTRAQ Combined with Liquid Chromatography-Mass Spectrometry.
Bai Y, Wang J, Gao Z, Dai E
Pathology oncology research : POR 2020 Apr;26(2):967-976
Pathology oncology research : POR 2020 Apr;26(2):967-976
Acetylation of Cytidine in mRNA Promotes Translation Efficiency.
Arango D, Sturgill D, Alhusaini N, Dillman AA, Sweet TJ, Hanson G, Hosogane M, Sinclair WR, Nanan KK, Mandler MD, Fox SD, Zengeya TT, Andresson T, Meier JL, Coller J, Oberdoerffer S
Cell 2018 Dec 13;175(7):1872-1886.e24
Cell 2018 Dec 13;175(7):1872-1886.e24
Unraveling Molecular Differences of Gastric Cancer by Label-Free Quantitative Proteomics Analysis.
Dai P, Wang Q, Wang W, Jing R, Wang W, Wang F, Azadzoi KM, Yang JH, Yan Z
International journal of molecular sciences 2016 Jan 21;17(1)
International journal of molecular sciences 2016 Jan 21;17(1)
Subcellular quantitative proteomic analysis reveals host proteins involved in human cytomegalovirus infection.
Chai F, Li HY, Wang W, Zhu XJ, Li Y, Wang S, Guo L, Zhang LK, Xiao G
Biochimica et biophysica acta 2015 Aug;1854(8):967-78
Biochimica et biophysica acta 2015 Aug;1854(8):967-78
Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions.
Cooper-Knock J, Walsh MJ, Higginbottom A, Robin Highley J, Dickman MJ, Edbauer D, Ince PG, Wharton SB, Wilson SA, Kirby J, Hautbergue GM, Shaw PJ
Brain : a journal of neurology 2014 Jul;137(Pt 7):2040-51
Brain : a journal of neurology 2014 Jul;137(Pt 7):2040-51
Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
Neumann M, Valori CF, Ansorge O, Kretzschmar HA, Munoz DG, Kusaka H, Yokota O, Ishihara K, Ang LC, Bilbao JM, Mackenzie IR
Acta neuropathologica 2012 Nov;124(5):705-16
Acta neuropathologica 2012 Nov;124(5):705-16
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 12770-1-AP(HNRNPD antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using HNRNPD antibody 12770-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 12770-1-AP(HNRNPD antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 12770-1-AP(HNRNPD antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
