BS4115

antibody from Bioworld Technology, Inc

Targeting: LIMK1 LIMK

Immunocytochemistry

Immunohistochemistry

Antibody data

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Validation data

Product number: BS4115 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS4115, RRID:AB_1663899
Product name: LIMK1 (phospho T508) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic phosphopeptide derived from human LIMK1 around the phosphorylation site of Threonine 508.
Description: Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

LIMK1 protein structure - BS4115 shown in red.