AP0290

antibody from Bioworld Technology, Inc

Targeting: PRKCA PKCA, PKCα

Immunohistochemistry

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Validation data

Product number: AP0290 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#AP0290, RRID:AB_2797472
Product name: PKC Ï« (phospho T638) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic phosphopeptide derived from human PKC Ï« around the phosphorylation site of Threonine 638.
Description: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (Ï«, ÉÇI, ÉÇII and ÎÛ) and novel (n) PKC isoforms (Ñ´, ÷, ø, »Ò and Ä²). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC Ñ´ and ÷ are independent of Ca2+.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

PRKCA protein structure - AP0290 shown in red.