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- Antigen structure
- References [2]
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- Flow cytometry [1]
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- Product number
- MAB2806 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CLEC4D/CLECSF8 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CLEC4D/CLECSF8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) CLECSF9, rhCLECSF13, rhOCIL, or rhOCILrp2 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
Q8WXI8- Isotype
- IgG
- Antibody clone number
- 413512
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references CD32a is a marker of a CD4 T-cell HIV reservoir harbouring replication-competent proviruses.
The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through Syk kinase.
Descours B, Petitjean G, López-Zaragoza JL, Bruel T, Raffel R, Psomas C, Reynes J, Lacabaratz C, Levy Y, Schwartz O, Lelievre JD, Benkirane M
Nature 2017 Mar 23;543(7646):564-567
Nature 2017 Mar 23;543(7646):564-567
The C-type lectin receptor CLECSF8 (CLEC4D) is expressed by myeloid cells and triggers cellular activation through Syk kinase.
Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD
The Journal of biological chemistry 2012 Jul 27;287(31):25964-74
The Journal of biological chemistry 2012 Jul 27;287(31):25964-74
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CLEC4D/CLECSF8 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Mouse Anti-Human CLEC4D/CLECSF8 Monoclonal Antibody (Catalog # MAB2806, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab')2 Secondary Antibody (Catalog # F0102B).
