BS2382

antibody from Bioworld Technology, Inc

Targeting: CDC42BPB KIAA1124, MRCKB

Immunohistochemistry

Antibody data

Submit

Validation data

Product number: BS2382 - Provider product page
Provider: Bioworld Technology, Inc
Proper citation: Bioworld Technology Cat#BS2382, RRID:AB_1662888
Product name: MRCKÉÇ (F1665) polyclonal antibody
Antibody type: Polyclonal
Antigen: Synthetic peptide, corresponding to amino acids 1630-1680 of Human MRCKÉÇ.
Description: Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinaserelated Cdc42-binding (DMPK-like) kinases-Ï« and ÉÇ (MRCK-Ï«, ÉÇ) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle Myosin light chain and influences Actin-Myosin contractility. MRCK-Ï« can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/Cofilin and to Actin cytoskeletal reorganization. MRCK-Ï« can also influence neurite outgrowth promoted by Cdc42 and Rac.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

CDC42BPB protein structure - BS2382 shown in red.