orb1467379

antibody from Biorbyt

Targeting: CLEC4A CD367, CLECSF6, DCIR, DDB27

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

orb1467379

Provider

Biorbyt

Product name

CD367 Antibody

Antibody type

Monoclonal

Description

CD367 is an approximately 20-28 kDa C-type lectin with immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic part. CD367 binds in calcium-dependent manner to mannose, fucose, and weakly also to N-acetylglucosamine. It is expressed on dendritic cells, macrophages, monocytes, B cells, and neutrophils. In rheumatoid arthitis patients CD367 is expressed also on CD4+ T cells. After ligand-mediated triggering, it is internalized by clathrin-dependent endocytosis and contributes to the antigen presentation to CD8+ T cells. It may also be involved in modulation of the antigen presenting cell response.

Reactivity

Human, Simian

Conjugate

Unconjugated

Antibody clone number

9E8

Vial size

0.1 mg

Concentration

1 mg/ml

Storage

Store at 2-8°C. Do not freeze.