BS60159

antibody from Bioworld Technology, Inc
Targeting: HPGDS GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS
Provider product page for BS60159

Antibody data

Product number
BS60159 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PGD synthase polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human PGD synthase.
Description
Human PGD synthase is the key enzyme for production of the D and J series of prostanoids in the immune system and mast cells. This enzyme is the first member of the sigma class glutathione S-transferases (GST) from vertebrates and contains a prominent cleft as the active site, which is unique among members of the GST superfamily. The human PGD synthase gene, which maps to chromosome 4q22.3, is expressed in a species-specific manner. For instance, the human gene is widely distributed, whereas the mouse gene is only expressed in oviduct and skin. Human PGD synthase is expressed in the cytoplasm of human megakaryoblastic CMK cells prior to differentiation into platelets, which have no PGD synthase activity. Another member of the PGD synthase family, PGD2 synthase, catalyzes the conversion of PGH2 to PGD2 and is essential for the synthesis of PGD2 in the brain. Unlike PGD synthase, PGD2 synthase is not dependent on the presence of glutathione for its activity.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HPGDS protein structure - BS60159 shown in red.