MAB866
antibody from R&D Systems
Targeting: CXCL14
BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14
Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- MAB866 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CXCL14/BRAK Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CXCL14/BRAK in ELISAs and Western blots. In direct ELISAs, shows approximately 80% cross-reactivity with recombinant mouse (rm) CXCL14/BRAK and no cross-reactivity with recombinant human (rh)GRO alpha , rhGRO beta , rhGRO gamma ,rhMIP-1 alpha , rmMIP-1 alpha , rmMIP-1 beta , rhMIP-1 delta , rmMIP-1 gamma , rmMIP-2, rhMIP-3 alpha , rmMIP-3 alpha , rrMIP-3 alpha , rhMIP-3 beta , or rmMIP-3 beta .
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
O95715
- Isotype
- IgG
- Antibody clone number
- 131120
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references The Expression of the Chemokine CXCL14 Correlates with Several Aggressive Aspects of Glioblastoma and Promotes Key Properties of Glioblastoma Cells.
Involvement of CXCL14 in osteolytic bone metastasis from lung cancer.
Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo.
Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo.
Fazi B, Proserpio C, Galardi S, Annesi F, Cola M, Mangiola A, Michienzi A, Ciafrè SA
International journal of molecular sciences 2019 May 21;20(10)
International journal of molecular sciences 2019 May 21;20(10)
Involvement of CXCL14 in osteolytic bone metastasis from lung cancer.
Takiguchi S, Korenaga N, Inoue K, Sugi E, Kataoka Y, Matsusue K, Futagami K, Li YJ, Kukita T, Teramoto N, Iguchi H
International journal of oncology 2014 Apr;44(4):1316-24
International journal of oncology 2014 Apr;44(4):1316-24
Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo.
Shurin GV, Ferris RL, Tourkova IL, Perez L, Lokshin A, Balkir L, Collins B, Chatta GS, Shurin MR
Journal of immunology (Baltimore, Md. : 1950) 2005 May 1;174(9):5490-8
Journal of immunology (Baltimore, Md. : 1950) 2005 May 1;174(9):5490-8
Loss of new chemokine CXCL14 in tumor tissue is associated with low infiltration by dendritic cells (DC), while restoration of human CXCL14 expression in tumor cells causes attraction of DC both in vitro and in vivo.
Shurin GV, Ferris RL, Tourkova IL, Perez L, Lokshin A, Balkir L, Collins B, Chatta GS, Shurin MR
Journal of immunology (Baltimore, Md. : 1950) 2005 May 1;174(9):5490-8
Journal of immunology (Baltimore, Md. : 1950) 2005 May 1;174(9):5490-8
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