Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
- Other assay [1]
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Validation data
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- Product number
- 46-7098-42 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- IL-9 Monoclonal Antibody (MH9D1), PerCP-eFluor™ 710, eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: The monoclonal antibody MH9D1 recognizes interleukin-9 (IL-9), a proinflammatory cytokine historically believed to be involved in type 2 immune responses. Recent evidence suggests IL-9 may instead be secreted by a distinct T-helper lineage called Th9. These cells can be derived from Th2 cells with TGF beta or differentiated directly from naive CD4+ T cells with TGF beta and IL-4.
- Antibody clone number
- MH9D1
- Concentration
- 5 µL/Test
Submitted references Increased circulating IL-9-producing CD8(+) T cells are associated with eosinophilia and high FeNO in allergic asthmatics.
Wang W, Cheng ZS, Chen YF, Lin YH
Experimental and therapeutic medicine 2016 Dec;12(6):4055-4060
Experimental and therapeutic medicine 2016 Dec;12(6):4055-4060
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Intracellular staining of Th9 polarized normal human peripheral blood cells stimulated in the presence of Cell Stimulation Cocktail (plus protein transport inhibitors) (Product # 00-4975-03) with Anti-Human CD4 FITC (Product # 11-0049-42) and Mouse IgG2a K Isotype Control PerCP-eFluor® 710 (Product # 46-4724-82) (left) or Anti-Human IL-9 PerCP-eFluor® 710 (right). Cells in the lymphocyte gate were used for analysis.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL