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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
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- Product number
- MAB2393 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB2393, RRID:AB_10697437
- Product name
- XRCC3 monoclonal antibody, clone 10F1/6
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against recombinant XRCC3.
- Isotype
- IgG
- Antibody clone number
- 10F1/6
- Storage
- Store at 4°C. Do not freeze.
Submitted references Dysfunctional homologous recombination mediates genomic instability and progression in myeloma.
WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening.
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance.
Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.
Increased MMP-2 expression in connective tissue growth factor over-expression vascular smooth muscle cells.
Shammas MA, Shmookler Reis RJ, Koley H, Batchu RB, Li C, Munshi NC
Blood 2009 Mar 5;113(10):2290-7
Blood 2009 Mar 5;113(10):2290-7
WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening.
Li B, Jog SP, Reddy S, Comai L
Molecular and cellular biology 2008 Mar;28(6):1892-904
Molecular and cellular biology 2008 Mar;28(6):1892-904
Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance.
Chan N, Koritzinsky M, Zhao H, Bindra R, Glazer PM, Powell S, Belmaaza A, Wouters B, Bristow RG
Cancer research 2008 Jan 15;68(2):605-14
Cancer research 2008 Jan 15;68(2):605-14
Xrcc3 and Nbs1 are required for the production of extrachromosomal telomeric circles in human alternative lengthening of telomere cells.
Compton SA, Choi JH, Cesare AJ, Ozgür S, Griffith JD
Cancer research 2007 Feb 15;67(4):1513-9
Cancer research 2007 Feb 15;67(4):1513-9
Increased MMP-2 expression in connective tissue growth factor over-expression vascular smooth muscle cells.
Fan WH, Karnovsky MJ
The Journal of biological chemistry 2002 Mar 22;277(12):9800-5
The Journal of biological chemistry 2002 Mar 22;277(12):9800-5
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- XRCC3 detected in HEK293 lysates using a 1 : 1,000 dilution of XRCC3 monoclonal antibody, clone 10F1/6 (Cat # MAB2393). Photo courtesy of B.T. Bennett & K. Knight of University of Massachusetts Medical School.
