Tissue expression
Cell line expression
Protein structure
FSCN1
Fascin actin-bundling protein 1FLJ38511, p55, SNL
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
Top validated antibodies |
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Proteintech Group | 14384-1-AP | 9 references | Polyclonal |
WB
EL
ICC
IHC
FC
|
|
Invitrogen Antibodies | 6624-MSM1-P0 | Monoclonal |
WB
ICC
IHC
FC
IEM
OA |
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Novus Biologicals | NBP2-66832 | Monoclonal |
WB
ICC
IP
IHC
FC
|
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antibodies-online | ABIN2840983 | 2 references | Polyclonal |
WB
IHC
FC
|
|
Boster Biological Technology | A02147-1 | Polyclonal |
WB
ICC
IP
IHC
FC
|
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Supportive data in Antibodypedia
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Recommended by provider