BS60800

antibody from Bioworld Technology, Inc
Targeting: ZNF462 DKFZP762N2316, KIAA1803, Zfp462
Provider product page for BS60800

Antibody data

Product number
BS60800 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ZNF462 polyclonal antibody
Antibody type
Polyclonal
Antigen
A synthetic peptide corresponding to residues in Human ZNF462.
Description
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr°îppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1,thereby recruiting histone modifying proteins. ZNF462 (zinc finger protein 462) is a 2,506 amino acid protein that localizes to nucleus and is subject to posttranslational phosphorylation upon DNA damage, possibly by ATM or ATR.Containing twenty-seven C2H2-type zinc finger motifs and existing as multiple alternatively spliced isoforms, ZNF462 is encoded by a gene located on human chromosome 9q31.2. Chromosome 9 consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects,and Familial dysautonomia, are both associated with chromosome 9.Notably, chromosome 9 encompasses the largest interferon family gene cluster.
Reactivity
Human, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ZNF462 protein structure - BS60800 shown in red.