APR05015G

antibody from Leading Biology
Targeting: ARHGEF7 BETA-PIX, COOL1, DKFZp686C12170, DKFZp761K1021, KIAA0142, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB
Provider product page for APR05015G
Western blot

Antibody data

Product number
APR05015G - Provider product page
Provider
Leading Biology
Product name
ARHGEF7 Antibody (C-Term)
Antibody type
Polyclonal
Description
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions (By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Reactivity
Human, Mouse
Host
Rabbit
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
ARHGEF7 protein structure - APR05015G shown in red.