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- Product number
- ABIN395929 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1) (AA 1-110) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-110
- Isotype
- IgG
- Antibody clone number
- 3D10
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Anaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cells.
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
F-actin-binding domain of c-Abl regulates localized phosphorylation of C3G: role of C3G in c-Abl-mediated cell death.
Identification of type 2 diabetes-associated combination of SNPs using support vector machine.
C3G silencing enhances STI-571-induced apoptosis in CML cells through p38 MAPK activation, but it antagonizes STI-571 inhibitory effect on survival.
Schönherr C, Yang HL, Vigny M, Palmer RH, Hallberg B
Oncogene 2010 May 13;29(19):2817-30
Oncogene 2010 May 13;29(19):2817-30
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR
Molecular medicine (Cambridge, Mass.) 2010 Jul-Aug;16(7-8):247-53
Molecular medicine (Cambridge, Mass.) 2010 Jul-Aug;16(7-8):247-53
F-actin-binding domain of c-Abl regulates localized phosphorylation of C3G: role of C3G in c-Abl-mediated cell death.
Mitra A, Radha V
Oncogene 2010 Aug 12;29(32):4528-42
Oncogene 2010 Aug 12;29(32):4528-42
Identification of type 2 diabetes-associated combination of SNPs using support vector machine.
Ban HJ, Heo JY, Oh KS, Park KJ
BMC genetics 2010 Apr 23;11:26
BMC genetics 2010 Apr 23;11:26
C3G silencing enhances STI-571-induced apoptosis in CML cells through p38 MAPK activation, but it antagonizes STI-571 inhibitory effect on survival.
Maia V, Sanz M, Gutierrez-Berzal J, de Luis A, Gutierrez-Uzquiza A, Porras A, Guerrero C
Cellular signalling 2009 Jul;21(7):1229-35
Cellular signalling 2009 Jul;21(7):1229-35
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
