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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB1978 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB1978, RRID:AB_1576435
- Product name
- JAG2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of JAG2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling.
Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction.
Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes.
Jagged2 induces cell cycling in confluent fibroblasts susceptible to density-dependent inhibition of cell division.
Cama A, Verginelli F, Lotti LV, Napolitano F, Morgano A, D'Orazio A, Vacca M, Perconti S, Pepe F, Romani F, Vitullo F, di Lella F, Visone R, Mannelli M, Neumann HP, Raiconi G, Paties C, Moschetta A, Tagliaferri R, Veronese A, Sanna M, Mariani-Costantini R
Acta neuropathologica 2013 Oct;126(4):575-94
Acta neuropathologica 2013 Oct;126(4):575-94
Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interaction.
Lindner V, Booth C, Prudovsky I, Small D, Maciag T, Liaw L
The American journal of pathology 2001 Sep;159(3):875-83
The American journal of pathology 2001 Sep;159(3):875-83
Requirement of Notch 1 and its ligand jagged 2 expressions for spermatogenesis in rat and human testes.
Hayashi T, Kageyama Y, Ishizaka K, Xia G, Kihara K, Oshima H
Journal of andrology 2001 Nov-Dec;22(6):999-1011
Journal of andrology 2001 Nov-Dec;22(6):999-1011
Jagged2 induces cell cycling in confluent fibroblasts susceptible to density-dependent inhibition of cell division.
Cereseto A, Tsai S
Journal of cellular physiology 2000 Dec;185(3):425-31
Journal of cellular physiology 2000 Dec;185(3):425-31
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of JAG2 (arrow) using JAG2 polyclonal antibody (Cat # PAB1978). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the JAG2 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with JAG2 polyclonal antibody (Cat # PAB1978) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
