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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS2359 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ILKAP (K71) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 40-90 of Human ILKAP.
- Description
- ILKAP (integrin-linked kinase-associated serine/threonine phosphatase 2C),also known as PP2CÑ´, is a 392 amino acid cytoplasmic protein phosphatase that selectively interacts with integrin linked kinase (ILK) to regulate growth factor signaling and cell adhesion. While widely expressed, ILKAP is found at highest levels in striated muscle with lower levels found in smooth muscle.ILKAP belongs to the PP2C family and contains one PP2C-like domain. ILKAP has been suggested to inhibit oncogenic transformation and the ILK-GSK3ÉÇsignaling axis, and can bind two magnesium or manganese ions per subunit as cofactors. The gene encoding ILKAP maps to human chromosome 2,which consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of ILKAP (K71) pAb at 1:500 dilutionLane1:HEK293T whole cell lysateLane2:sp2/0 whole cell lysateLane3:H9C2 whole cell lysate
