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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB839P-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human IL-12 R beta 1 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human IL-12 R beta 1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse IL-12 R beta 1 is observed.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P42701- Isotype
- IgG
- Antibody clone number
- 69310
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references IL-21 in the bone marrow microenvironment contributes to IgM secretion and proliferation of malignant cells in Waldenstrom macroglobulinemia.
A novel form of complete IL-12/IL-23 receptor beta1 deficiency with cell surface-expressed nonfunctional receptors.
Hodge LS, Ziesmer SC, Yang ZZ, Secreto FJ, Gertz MA, Novak AJ, Ansell SM
Blood 2012 Nov 1;120(18):3774-82
Blood 2012 Nov 1;120(18):3774-82
A novel form of complete IL-12/IL-23 receptor beta1 deficiency with cell surface-expressed nonfunctional receptors.
Fieschi C, Bosticardo M, de Beaucoudrey L, Boisson-Dupuis S, Feinberg J, Santos OF, Bustamante J, Levy J, Candotti F, Casanova JL
Blood 2004 Oct 1;104(7):2095-101
Blood 2004 Oct 1;104(7):2095-101
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of IL-12 R beta 1 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) treated with 5 μg/mL PHA for 48 hours or (B) untreated were stained with Mouse Anti-Human IL-12 R beta 1 PE-conjugated Monoclonal Antibody (Catalog # FAB839P) and Mouse Anti-Human CD3 epsilon APC-conjugated Monoclonal Antibody (Catalog # FAB100A). Quadrant markers were set based on control antibody staining (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.
