Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS2074 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS2074, RRID:AB_1663225
- Product name
- C/EBP ÷ (K220) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 188-245 of Human C/EBP-÷.
- Description
- C/EBP Ï« regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP Ï« uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic Ï« helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP Ï« appears to function exclusively in terminally-differentiated, growth-arrested cells. Additional family members include C/EBP ÉÇ, C/EBP ÎÛ, C/EBP Ñ´ and C/EBP ÷, all of which exhibit similar DNA-binding specificities and affinities to C/EBP Ï«. Furthermore, C/EBP ÉÇ and C/EBP Ñ´ readily form heterodimers both with each other as well as with C/EBP Ï«.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot (WB) analysis of C/EBP-¦Å (K220) pAb at 1:500 dilutionLane1:Hela cell lysateLane2:Raw264.7 cell lysateLane3:Rat kidney tissue lysate