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Learn15193-1-AP
antibody from Proteintech Group
Targeting: SLC3A2
4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 15193-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15193-1-AP, RRID:AB_2254909
- Product name
- CD98/SLC3A2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CD98/SLC3A2 antibody (Cat. #15193-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Brown adipocyte ATF4 activation improves thermoregulation and systemic metabolism.
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
Mast cell surfaceome characterization reveals CD98 heavy chain is critical for optimal cell function.
Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer.
Prolactin regulates LAT1 expression via STAT5 (signal transducer and activator of transcription 5) signaling in mammary epithelial cells of dairy cows.
SLC3A2 is upregulated in human osteosarcoma and promotes tumor growth through the PI3K/Akt signaling pathway.
Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression.
Upregulation of CD147 protects hepatocellular carcinoma cell from apoptosis through glycolytic switch via HIF-1 and MCT-4 under hypoxia.
CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway.
Paulo E, Zhang Y, Masand R, Huynh TL, Seo Y, Swaney DL, Soucheray M, Stevenson E, Jimenez-Morales D, Krogan NJ, Wang B
Cell reports 2021 Sep 21;36(12):109742
Cell reports 2021 Sep 21;36(12):109742
ZnO NPs delay the recovery of psoriasis-like skin lesions through promoting nuclear translocation of p-NFκB p65 and cysteine deficiency in keratinocytes.
Lai X, Wang M, Zhu Y, Feng X, Liang H, Wu J, Nie L, Li L, Shao L
Journal of hazardous materials 2021 May 15;410:124566
Journal of hazardous materials 2021 May 15;410:124566
Mast cell surfaceome characterization reveals CD98 heavy chain is critical for optimal cell function.
Saha SS, Samanas NB, Miralda I, Shubin NJ, Niino K, Bhise G, Acharya M, Seo AJ, Camp N, Deutsch GH, James RG, Piliponsky AM
The Journal of allergy and clinical immunology 2021 Jul 27;
The Journal of allergy and clinical immunology 2021 Jul 27;
Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer.
Sugiura M, Sato H, Okabe A, Fukuyo M, Mano Y, Shinohara KI, Rahmutulla B, Higuchi K, Maimaiti M, Kanesaka M, Imamura Y, Furihata T, Sakamoto S, Komiya A, Anzai N, Kanai Y, Luo J, Ichikawa T, Kaneda A
Translational oncology 2021 Jan;14(1):100915
Translational oncology 2021 Jan;14(1):100915
Prolactin regulates LAT1 expression via STAT5 (signal transducer and activator of transcription 5) signaling in mammary epithelial cells of dairy cows.
Zhou J, Jiang M, Shi Y, Song S, Hou X, Lin Y
Journal of dairy science 2020 Jul;103(7):6627-6634
Journal of dairy science 2020 Jul;103(7):6627-6634
SLC3A2 is upregulated in human osteosarcoma and promotes tumor growth through the PI3K/Akt signaling pathway.
Zhu B, Cheng D, Hou L, Zhou S, Ying T, Yang Q
Oncology reports 2017 May;37(5):2575-2582
Oncology reports 2017 May;37(5):2575-2582
Dominant Suppression of β1 Integrin by Ectopic CD98-ICD Inhibits Hepatocellular Carcinoma Progression.
Wu B, Zhou Y, Wang Y, Yang XM, Liu ZY, Li JH, Feng F, Chen ZN, Jiang JL
International journal of molecular sciences 2016 Nov 10;17(11)
International journal of molecular sciences 2016 Nov 10;17(11)
Upregulation of CD147 protects hepatocellular carcinoma cell from apoptosis through glycolytic switch via HIF-1 and MCT-4 under hypoxia.
Ke X, Chen Y, Wang P, Xing J, Chen Z
Hepatology international 2014 Jul;8(3):405-14
Hepatology international 2014 Jul;8(3):405-14
CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway.
Fei F, Li X, Xu L, Li D, Zhang Z, Guo X, Yang H, Chen Z, Xing J
Annals of surgical oncology 2014 Dec;21(13):4359-68
Annals of surgical oncology 2014 Dec;21(13):4359-68
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15193-1-AP(SLC3A2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using SLC3A2 antibody 15193-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 15193-1-AP(SLC3A2 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 15193-1-AP(SLC3A2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
