PAB14670

antibody from Abnova Corporation

Targeting: BIRC7 KIAP, ML-IAP, mliap, RNF50

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB14670

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB14670, RRID:AB_10550828

Product name

BIRC7 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of BIRC7.

Antigen sequence

PELPTPRREVQSESAQEPG


Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Isoform-specific silencing of the Livin gene by RNA interference defines Livin beta as key mediator of apoptosis inhibition in HeLa cells.

Crnković-Mertens I, Semzow J, Hoppe-Seyler F, Butz K
Journal of molecular medicine (Berlin, Germany) 2006 Mar;84(3):232-40

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Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function.

Wright CW, Duckett CS
The Journal of clinical investigation 2005 Oct;115(10):2673-8

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Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma.

Nachmias B, Ashhab Y, Bucholtz V, Drize O, Kadouri L, Lotem M, Peretz T, Mandelboim O, Ben-Yehuda D
Cancer research 2003 Oct 1;63(19):6340-9

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Western blot analysis of full-length, recombinant human BIRC7 using BIRC7 polyclonal antibody (Cat #PAB14670) at 1 : 2000.

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemical analysis of BIRC7 in formalin-fixed, paraffin embedded human tonsil (secondary nodule) using BIRC7 polyclonal antibody (Cat #PAB14670) at 1 : 2000. Hematoxylin-eosin counterstain.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunohistochemical analysis of BIRC7 in Bouin's-fixed, paraffin-embedded E13.5 mouse embryo (13.5 days post coitum) Bouin's using BIRC7 polyclonal antibody (Cat #PAB14670) at 1 : 2000. The mother was perfused prior to embryo harvesting. A, brain overview. B, brain. C, spinal cord. D, liver and abdominal wall. Hematoxylin-eosin counterstain.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)