ADI-AAP-240-D

antibody from Enzo Life Sciences

Targeting: MCL1 BCL2L3, Mcl-1

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

ADI-AAP-240-D

Provider

Enzo Life Sciences

Product name

Mcl-1 polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide

Description

Peptide affinity purified.

Reactivity

Human, Canine, Guinea Pig, Porcine, Rabbit, Simian

Host

Rabbit

Vial size

50 μg

Storage

-20°C

Handling

Avoid freeze/thaw cycles.

References

Submitted references

Low expression of pro-apoptotic Bcl-2 family proteins sets the apoptotic threshold in Waldenström macroglobulinemia.

Gaudette BT, Dwivedi B, Chitta KS, Poulain S, Powell D, Vertino P, Leleu X, Lonial S, Chanan-Khan AA, Kowalski J, Boise LH
Oncogene 2016 Jan 28;35(4):479-90

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Critical role of mitochondria-mediated apoptosis for JNJ-26481585-induced antitumor activity in rhabdomyosarcoma.

Heinicke U, Kupka J, Fichter I, Fulda S
Oncogene 2015 Nov 30;

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Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs.

Hugle M, Belz K, Fulda S
Cell death and differentiation 2015 Dec;22(12):1946-56

Immunocytochemistry

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Western blot analysis of Mcl-1, pAb: Lane 1: MW marker, Lane 2: HeLa, Lane 3: 3T3, Lane 4: PC-12, Lane 5: MDCK, Lane 6: RK-13.

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Immunohistochemistry analysis of human breast cancer tissue with Mcl-1 pAb.

Supportive validation

Submitted by

Enzo Life Sciences (provider)

Main image

Experimental details

Immunofluorescent analysis (confocal) staining of HeLa cells using Mcl-1 pAb (green); nuclei are stained in blue pseudocolor using DRAQ5.