MAB2710

antibody from Abnova Corporation

Targeting: PTPRN IA-2, ICA512

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

MAB2710

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#MAB2710, RRID:AB_10633568

Product name

PTPRN monoclonal antibody, clone AFT38

Antibody type

Monoclonal

Description

Mouse monoclonal antibody raised against recombinant PTPRN.

Antibody clone number

AFT38

Storage

Store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

ICA512 signaling enhances pancreatic beta-cell proliferation by regulating cyclins D through STATs.

Mziaut H, Kersting S, Knoch KP, Fan WH, Trajkovski M, Erdmann K, Bergert H, Ehehalt F, Saeger HD, Solimena M
Proceedings of the National Academy of Sciences of the United States of America 2008 Jan 15;105(2):674-9

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Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2.

Primo ME, Klinke S, Sica MP, Goldbaum FA, Jakoncic J, Poskus E, Ermácora MR
The Journal of biological chemistry 2008 Feb 22;283(8):4674-81

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RESP18, a homolog of the luminal domain IA-2, is found in dense core vesicles in pancreatic islet cells and is induced by high glucose.

Zhang G, Hirai H, Cai T, Miura J, Yu P, Huang H, Schiller MR, Swaim WD, Leapman RD, Notkins AL
The Journal of endocrinology 2007 Nov;195(2):313-21

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Immunoblot analysis of cell lysates.Lane 1 : Bosc23 cell lysate.Lane 2 : Bosc23 cell lysate transfected with Myc/His/Tau (1-441 a. a.).Lane 3 : Bosc23 cell lysate transfected with Myc/His/PTPRN (709-979 a. a.).Lane 4 : Bosc23 cell lysate transfected with GFP-Ubiquitin+1.