Antibody data

Product number
BS2633
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS2633, RRID:AB_1662634
Product name
NK 2R (P340) polyclonal antibody
Provider product page
Bioworld Technology, Inc - BS2633
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 320-370 of Human NK-2R.
Description
Substance P (SP) and neurokinin-A (NK-A) are members of the tachykinins, and they function as modulators of the immune and hematopoietic systems. The tachykinins interact with each of three cloned neurokinin (NK) receptors (NK-1R, NK-2R, NK-3R), with SP and NK-A exhibiting binding preferences for NK-1R and NK-2R, respectively. NK-4R shares close homology with NK-3R, and both have nearly identical pharmacologicl properties. In the normal ileum and colon, NK-1R and NK-2R are localized to smooth muscle cells of the muscularis mucosae and propria and to a few inflammatory cells of the lamina propria. NK-1R expression is also found in the muscular wall of submucosal blood vessels, enteric neurons and, to a lesser degree, in surface epithelial cells. NK-3R is found in the spinal cord in both lamina X and lamina II.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Provider Type Product Number
- No reagents -