Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15492-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15492-1-AP, RRID:AB_2140752
- Product name
- MARK2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MARK2 antibody (Cat. #15492-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A mechanism that transduces lysosomal damage signals to stress granule formation for cell survival.
Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways.
MARK2 and MARK4 Regulate Sertoli Cell BTB Dynamics Through Microtubule and Actin Cytoskeletons.
Molecular determinants of αVβ5 localization in flat clathrin lattices - role of αVβ5 in cell adhesion and proliferation.
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.
The Non-hormonal Male Contraceptive Adjudin Exerts its Effects via MAPs and Signaling Proteins mTORC1/rpS6 and FAK-Y407.
NC1-Peptide From Collagen α3 (IV) Chains in the Basement Membrane of Testes Regulates Spermatogenesis via p-FAK-Y407.
CAMSAP2 Is a Microtubule Minus-End Targeting Protein That Regulates BTB Dynamics Through Cytoskeletal Organization.
Loss of Par1b/MARK2 primes microglia during brain development and enhances their sensitivity to injury.
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
Basement Membrane Laminin α2 Regulation of BTB Dynamics via Its Effects on F-Actin and Microtubule Cytoskeletons Is Mediated Through mTORC1 Signaling.
An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.
Duran J, Poolsup S, Allers L, Lemus MR, Cheng Q, Pu J, Salemi M, Phinney B, Jia J
bioRxiv : the preprint server for biology 2024 Apr 2;
bioRxiv : the preprint server for biology 2024 Apr 2;
Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways.
Song Z, Mao H, Liu J, Sun W, Wu S, Lu X, Jin C, Yang J
Cellular and molecular neurobiology 2023 Apr;43(3):1181-1196
Cellular and molecular neurobiology 2023 Apr;43(3):1181-1196
MARK2 and MARK4 Regulate Sertoli Cell BTB Dynamics Through Microtubule and Actin Cytoskeletons.
Tang EI, Cheng CY
Endocrinology 2022 Oct 11;163(11)
Endocrinology 2022 Oct 11;163(11)
Molecular determinants of αVβ5 localization in flat clathrin lattices - role of αVβ5 in cell adhesion and proliferation.
Zuidema A, Wang W, Kreft M, Bleijerveld OB, Hoekman L, Aretz J, Böttcher RT, Fässler R, Sonnenberg A
Journal of cell science 2022 Jun 1;135(11)
Journal of cell science 2022 Jun 1;135(11)
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.
Chan TY, Egbert CM, Maxson JE, Siddiqui A, Larsen LJ, Kohler K, Balasooriya ER, Pennington KL, Tsang TM, Frey M, Soderblom EJ, Geng H, Müschen M, Forostyan TV, Free S, Mercenne G, Banks CJ, Valdoz J, Whatcott CJ, Foulks JM, Bearss DJ, O'Hare T, Huang DCS, Christensen KA, Moody J, Warner SL, Tyner JW, Andersen JL
Nature communications 2021 Sep 9;12(1):5337
Nature communications 2021 Sep 9;12(1):5337
The Non-hormonal Male Contraceptive Adjudin Exerts its Effects via MAPs and Signaling Proteins mTORC1/rpS6 and FAK-Y407.
Wang L, Yan M, Li H, Wu S, Ge R, Wong CKC, Silvestrini B, Sun F, Cheng CY
Endocrinology 2021 Jan 1;162(1)
Endocrinology 2021 Jan 1;162(1)
NC1-Peptide From Collagen α3 (IV) Chains in the Basement Membrane of Testes Regulates Spermatogenesis via p-FAK-Y407.
Li H, Liu S, Wu S, Ge R, Cheng CY
Endocrinology 2020 Oct 1;161(10)
Endocrinology 2020 Oct 1;161(10)
CAMSAP2 Is a Microtubule Minus-End Targeting Protein That Regulates BTB Dynamics Through Cytoskeletal Organization.
Mao BP, Li L, Ge R, Li C, Wong CKC, Silvestrini B, Lian Q, Cheng CY
Endocrinology 2019 Jun 1;160(6):1448-1467
Endocrinology 2019 Jun 1;160(6):1448-1467
Loss of Par1b/MARK2 primes microglia during brain development and enhances their sensitivity to injury.
DiBona VL, Zhu W, Shah MK, Rafalia A, Ben Cheikh H, Crockett DP, Zhang H
Journal of neuroinflammation 2019 Jan 17;16(1):11
Journal of neuroinflammation 2019 Jan 17;16(1):11
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
Gao Y, Mruk D, Chen H, Lui WY, Lee WM, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
Basement Membrane Laminin α2 Regulation of BTB Dynamics via Its Effects on F-Actin and Microtubule Cytoskeletons Is Mediated Through mTORC1 Signaling.
Gao Y, Chen H, Lui WY, Lee WM, Cheng CY
Endocrinology 2017 Apr 1;158(4):963-978
Endocrinology 2017 Apr 1;158(4):963-978
An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential.
Goodwin JM, Svensson RU, Lou HJ, Winslow MM, Turk BE, Shaw RJ
Molecular cell 2014 Aug 7;55(3):436-50
Molecular cell 2014 Aug 7;55(3):436-50
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 15492-1-AP(MARK2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human brain using 15492-1-AP(MARK2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MARK2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human MARK2. This antibody recognizes human,mouse,rat antigen. The MARK2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.