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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12275-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12275-1-AP, RRID:AB_2225096
- Product name
- AGR2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated AGR2 antibody (Cat. #12275-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia.
Early administration of dapagliflozin preserves pancreatic β-cell mass through a legacy effect in a mouse model of type 2 diabetes.
Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study.
Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation.
Identification and prognostic value of anterior gradient protein 2 expression in breast cancer based on tissue microarray.
Unique recurrence patterns of cervical intraepithelial neoplasia after excision of the squamocolumnar junction.
Cervical squamocolumnar junction-specific markers define distinct, clinically relevant subsets of low-grade squamous intraepithelial lesions.
A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia.
A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer.
Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach.
Chumduri C, Gurumurthy RK, Berger H, Dietrich O, Kumar N, Koster S, Brinkmann V, Hoffmann K, Drabkina M, Arampatzi P, Son D, Klemm U, Mollenkopf HJ, Herbst H, Mangler M, Vogel J, Saliba AE, Meyer TF
Nature cell biology 2021 Feb;23(2):184-197
Nature cell biology 2021 Feb;23(2):184-197
Early administration of dapagliflozin preserves pancreatic β-cell mass through a legacy effect in a mouse model of type 2 diabetes.
Kanno A, Asahara SI, Kawamura M, Furubayashi A, Tsuchiya S, Suzuki E, Takai T, Koyanagi-Kimura M, Matsuda T, Okada Y, Ogawa W, Kido Y
Journal of diabetes investigation 2019 May;10(3):577-590
Journal of diabetes investigation 2019 May;10(3):577-590
Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study.
Negi H, Merugu SB, Mangukiya HB, Li Z, Zhou B, Sehar Q, Kamle S, Yunus FU, Mashausi DS, Wu Z, Li D
Cancer letters 2019 May 1;449:125-134
Cancer letters 2019 May 1;449:125-134
Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation.
Maurel M, Obacz J, Avril T, Ding YP, Papadodima O, Treton X, Daniel F, Pilalis E, Hörberg J, Hou W, Beauchamp MC, Tourneur-Marsille J, Cazals-Hatem D, Sommerova L, Samali A, Tavernier J, Hrstka R, Dupont A, Fessart D, Delom F, Fernandez-Zapico ME, Jansen G, Eriksson LA, Thomas DY, Jerome-Majewska L, Hupp T, Chatziioannou A, Chevet E, Ogier-Denis E
EMBO molecular medicine 2019 Jun;11(6)
EMBO molecular medicine 2019 Jun;11(6)
Identification and prognostic value of anterior gradient protein 2 expression in breast cancer based on tissue microarray.
Guo J, Gong G, Zhang B
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317713392
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317713392
Unique recurrence patterns of cervical intraepithelial neoplasia after excision of the squamocolumnar junction.
Herfs M, Somja J, Howitt BE, Suarez-Carmona M, Kustermans G, Hubert P, Doyen J, Goffin F, Kridelka F, Crum CP, Delvenne P
International journal of cancer 2015 Mar 1;136(5):1043-52
International journal of cancer 2015 Mar 1;136(5):1043-52
Cervical squamocolumnar junction-specific markers define distinct, clinically relevant subsets of low-grade squamous intraepithelial lesions.
Herfs M, Parra-Herran C, Howitt BE, Laury AR, Nucci MR, Feldman S, Jimenez CA, McKeon FD, Xian W, Crum CP
The American journal of surgical pathology 2013 Sep;37(9):1311-8
The American journal of surgical pathology 2013 Sep;37(9):1311-8
A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia.
Herfs M, Vargas SO, Yamamoto Y, Howitt BE, Nucci MR, Hornick JL, McKeon FD, Xian W, Crum CP
The Journal of pathology 2013 Feb;229(3):460-8
The Journal of pathology 2013 Feb;229(3):460-8
A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer.
Herfs M, Yamamoto Y, Laury A, Wang X, Nucci MR, McLaughlin-Drubin ME, Münger K, Feldman S, McKeon FD, Xian W, Crum CP
Proceedings of the National Academy of Sciences of the United States of America 2012 Jun 26;109(26):10516-21
Proceedings of the National Academy of Sciences of the United States of America 2012 Jun 26;109(26):10516-21
Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach.
Xue H, Lü B, Zhang J, Wu M, Huang Q, Wu Q, Sheng H, Wu D, Hu J, Lai M
Journal of proteome research 2010 Jan;9(1):545-55
Journal of proteome research 2010 Jan;9(1):545-55
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse stomach tissue were subjected to SDS PAGE followed by western blot with 12275-1-AP(AGR2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AGR2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AGR2. This antibody recognizes human,mouse,rat antigen. The AGR2 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
