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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- PAB4864 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4864, RRID:AB_1571228
- Product name
- AGR2 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of AGR2.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Increased expression of anterior gradient-2 is significantly associated with poor survival of prostate cancer patients.
Physiological stress induces the metastasis marker AGR2 in breast cancer cells.
hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.
Zhang Y, Forootan SS, Liu D, Barraclough R, Foster CS, Rudland PS, Ke Y
Prostate cancer and prostatic diseases 2007;10(3):293-300
Prostate cancer and prostatic diseases 2007;10(3):293-300
Physiological stress induces the metastasis marker AGR2 in breast cancer cells.
Zweitzig DR, Smirnov DA, Connelly MC, Terstappen LW, O'Hara SM, Moran E
Molecular and cellular biochemistry 2007 Dec;306(1-2):255-60
Molecular and cellular biochemistry 2007 Dec;306(1-2):255-60
hAG-2 and hAG-3, human homologues of genes involved in differentiation, are associated with oestrogen receptor-positive breast tumours and interact with metastasis gene C4.4a and dystroglycan.
Fletcher GC, Patel S, Tyson K, Adam PJ, Schenker M, Loader JA, Daviet L, Legrain P, Parekh R, Harris AL, Terrett JA
British journal of cancer 2003 Feb 24;88(4):579-85
British journal of cancer 2003 Feb 24;88(4):579-85
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of AGR2 (arrow) using rabbit AGR2 polyclonal antibody (Cat # PAB4864). 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AGR2 gene (Lane 2) (Origene Technologies).
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of AGR2 polyclonal antibody (Cat # PAB4864) in T-47D cell lysate (35 ug/lane). AGR2 (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with AGR2 polyclonal antibody (Cat # PAB4864) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
