CABT-BL1095

antibody from Creative Diagnostics

Targeting: CLPS

Western blot (Recommended by provider)

Antibody Data

Product number

CABT-BL1095

Provider

Creative Diagnostics

Product name

Anti-CLPS monoclonal antibody, clone EML097

Antibody type

Monoclonal

Description

The protein encoded by this gene is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG