abx010851

antibody from Abbexa

Targeting: GRIA2 GluA2, GLUR2, GLURB

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx010851

Provider

Abbexa

Product name

Glutamate Receptor 2 (GRIA2) Antibody

Antibody type

Monoclonal

Description

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca (2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

1 mg/ml

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.